产品货号:
Z24420
中文名称:
PTCH2抗体
英文名称:
Anti-PTCH2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PTCH2 Antibody |
指标别名 | patched homolog 2 (Drosophila);Protein patched homolog 2;PTC2;PTCH2 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | WB |
基因名称 | PTCH2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human PTCH2(885-901aa WLHDKYDTTGENLRIPP),different from the related mouse sequence by one amino acid. |
实际分子量 | 131KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | PTCH2(patched 2),also known as PTC2,encodes a 1.203-amino acid putative transmembrane protein that is highly homologous to the PTCH product.The Patched-hedgehog signaling pathway is involved in establishing segment polarity and the anterior-posterior orientation of a number of developing appendages.The pathway is conserved from fly to vertebrates and has been implicated in a number of human neoplasms and developmental syndromes.Mutations in the human Patched gene are the basis of the nevoid basal cell carcinoma syndrome.With age,homozygous mutant male mice developed skin lesions consisting of alopecia and epidermal hyperplasia,suggesting a role for Ptch2 in adult epidermal homeostasis via Shh signaling. |
Uniprot ID | Q9Y6C5 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | patched 2 |
蛋白名全称 | Protein patched homolog 2(PTC2) |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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